We investigated the co-event and exclusivity of mutations in the exact same cancer gene pairs across all most cancers types. Curiously, we located that selected gene pairs exhibit distinctive mutation designs in different cancer varieties. As an illustration, we observed that mutations within the TP53 This is particularly intriguing provided that

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less than both Drake’s and Lynch’s designs, the price of deleterious mutations is exactly what drives mutation rates down (Drake 1991; Lynch 2010; Sung et al. 2012). Therefore, less than each products, a rise in the typical expense of mutations would produce a minimize in mutation prices. to look at this, Drake examined mutation costs of thermo

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